Journal club

 

We host a journal club once every two weeks on Wednesdays at 11.30-12.30 am. A member of the Landry lab will select a single paper of interest and then discuss it with the attendees.  The journal club is very informal, and all members of IBIS are welcome to attend!

If you would like to subscribe to the mailing list for this journal club, please follow the instructions here. Please direct any queries regarding the journal club to: Simon Aubé

Wednesday 26th October, 2022

Fitness Landscape Analysis of a tRNA Gene Reveals that the Wild Type Allele is Sub-optimal, Yet Mutationally Robust

Tzahi Gabzi, Yitzhak Pilpel, Tamar Friedlander

Molecular Biology and Evolution

Responsible for the discussion: Christian Landry

Wednesday 28th September, 2022

Mutation bias reflects natural selection in Arabidopsis thaliana

J Grey Monroe, Thanvi Srikant, Pablo Carbonell-Bejerano, Claude Becker, Mariele Lensink, Moises Exposito-Alonso, Marie Klein, Julia Hildebrandt, Manuela Neumann, Daniel Kliebenstein, Mao-Lun Weng, Eric Imbert, Jon Ågren, Matthew T Rutter, Charles B Fenster, Detlef Weigel

Nature

Responsible for the discussion: Simon Aubé

Tuesday 19th April, 2022

Contingency and selection in mitochondrial genome dynamics

Christopher J Nunn, Sidhartha Goyal

eLife

Responsible for the discussion: Damien Biot-Pelletier

Tuesday 5th April, 2022

Expression level is a major modifier of the fitness landscape of a protein coding gene

Zhuoxing Wu, Xiujuan Cai, Xin Zhang, Yao Liu, Guo-bao Tian, Jian-Rong Yang, Xiaoshu Chen

Nature Ecology & Evolution

Responsible for the discussion: Angel Cisneros

 

Tuesday 22nd March, 2022

Domestication of the Emblematic White Cheese-Making Fungus Penicillium camemberti and Its Diversification into Two Varieties

Jeanne Ropars, Estelle Didiot, Ricardo C. Rodríguez de la Vega, Bastien Bennetot, Monika Coton, Elisabeth Poirier, Emmanuel Coton, Alodie Snirc, Stéphanie Le Prieur, Tatiana Giraud

Current Biology

Responsible for the discussion: Emilie Alexander

Wednesday 9th March, 2022

Acquisition of cross-azole tolerance and aneuploidy in Candida albicans strains evolved to posaconazole

Rebekah J. Kukurudz, Madison Chapel, Quinn Wonitowy, Abdul-Rahman Adamu Bukari, Brooke Sidney, Riley Sierhuis, Aleeza C. Gerstein

bioRxiv

Responsible for the discussion: Camille Bédard

Tuesday 22nd February, 2022

Co-option of the same ancestral gene family gave rise to mammalian and reptilian toxins

Agneesh Barrua, Ivan Koludarov, Alexander S. Mikheyev

BMC Biology

Responsible for the discussion: Pascale Lemieux

Tuesday 8th February, 2022

A computational exploration of resilience and evolvability of protein–protein interaction networks

Brennan Klein, Ludvig Holmér, Keith M Smith, Mackenzie M Johnson, Anshuman Swain, Laura Stolp, Ashley I Teufel, April S Kleppe

Communications Biology

Responsible for the discussion: Simon Aubé

Tuesday 25th January, 2022

Climbing Up and Down Binding Landscapes through Deep Mutational Scanning of Three Homologous Protein-Protein Complexes

 

Michael Heyne, Jason Shirian, Itay Cohen, Yoav Peleg, Evette S. Radisky, Niv Papo, Julia M. Shifman

J. Am. Chem. Soc.

Responsible for the discussion: Soham Dibyachintan

 

Tuesday 11th January, 2022

An in vitro system to silence mitochondrial gene expression

 

Luis Daniel Cruz -Zaragoza, Sven Dennerlein, Andreas Linden, Roya Yousefi, Elena Lavdovskaia, Abhishek Aich, Rebecca R.Falk, Ridhima Gomkale, Thomas Schöndorf, Markus T.Bohnsack, Ricarda Richter-Dennerlein, Henning Urlaub, Peter Rehling
doi: https://doi.org/10.1016/j.cell.2021.09.033

Cell

Responsible for the discussion: Damien Biot-Pelletier

 

Wednesday 8th December, 2021

Herpesviruses assimilate kinesin to produce motorized viral particles

 

Caitlin E. Pegg, Sofia V. Zaichick, Ewa Bomba-Warczak, Vladimir Jovasevic, DongHo Kim, Himanshu Kharkwal, Duncan W. Wilson, Derek Walsh, Patricia J. Sollars, Gary E. Pickard, Jeffrey N. Savas, Gregory A. Smith
doi: https://doi.org/10.1038/s41586-021-04106-w

Nature

Responsible for the discussion: David Jordan

Wednesday 24th November, 2021

The structure of genotype-phenotype maps makes fitness landscapes navigable

Sam F. Greenbury, Ard A. Louis, Sebastian E. Ahnert
doi: https://doi.org/10.1101/2021.10.11.463990

bioRxiv

Responsible for the discussion: Alicia Pageau

 

Wednesday 10th November, 2021

Circular RNA repertoires are associated with evolutionarily young transposable elements

                                                                                  Franziska Gruhl, Peggy Janich, Henrik Kaessmann, David Gatfield
doi: https://elifesciences.org/articles/67991

eLife

Responsible for the discussion: Daniel Evans-Yamamoto

 

The lab

The Landry lab is located at the Institut de Biologie Intégrative et des Systèmes (IBIS) of Université Laval and is part of the Quebec Network for Research on Protein Function, Engineering, and Applications (PROTEO). IBIS and PROTEO offer very stimulating training environments and cutting edge technologies. The Landry lab is an international team of 28 students, PDFs and research associates from different backgrounds (microbiology, biology, bioinformatics, biochemistry) addressing questions in evolutionary cell and systems biology.
The lab