Daniel Evans-Yamamoto

PhD student / Evolutionary systems biology


I have spent most of my young years in Tokyo, where I started an undergraduate degree in Keio University. There I joined Dr. Nozomu Yachie’s laboratory at The University of Tokyo and worked on protein-protein interaction screenings and DNA barcoding as a research student. In 2016, Dr. Christian Landry visited us during his sabbatical, where I grew my interest in evolutionary systems biology and started collaborating. While still being affiliated to Keio university, I obtained my master’s degree under Dr. Nozomu Yachie’s supervision. I joined the Landry laboratory to further accelerate the collaboration in my first year of PhD..


Research interests

My research interest lies in how alterations to protein sequences can affect the interactions of proteins. To tackle this question, I take approaches to experimentally compare interactions of proteins by screening protein variants. In order to efficiently screen such interactions, I have also been keen on technology development using DNA barcodes. I also like to keep an eye open for new technologies in the biology field.


Evans-Yamamoto D, Rouleau FD, Nanda P, Makanae K, Liu Y, Després PC, Matsuo H, Seki M, Dubé AK, Ascencio D, Yachie N, and Landry CR. Barcode fusion genetics-protein-fragment complementation assay (BFG-PCA): tools and resources that expand the potential for binary protein interaction discovery. Nucleic Acids Research, gkac045 (2022) 

Suzuki G, Saito Y, Seki M, Evans-Yamamoto D, Negishi M, Kakoi K, Kawai H, Landry CR, Yachie N, and Mitsuyama T. Machine learning approach for discrimination of genotypes based on bright-field cellular images. npj Systems Biology and Applications 7, Article number: 31 (2021) 

Murai Y, Masuda T, Onuma Y, Evans-Yamamoto D, Takeuchi N, Mori H, Masuyama N, Ishiguro S, Yachie N, Arakawa K. Complete Genome Sequence of Bacillus sp. Strain KH172YL63, Isolated from Deep-Sea Sediment. Microbiology Resource Announcements 9:e00291-20 (2019)

Marchant A, Cisneros A, Dubé A, Gagnon-Arsenault I, Ascencio D, Jain H, Aubé S, Eberlein C, Evans-Yamamoto D, Yachie N & Landry C, The role of structural pleiotropy and regulatory evolution in the retention of heteromers of paralogs. eLife 8: e46754 (2019)

Evans-Yamamoto D*, Takeuchi N*, Masuda T, Murai Y, Onuma Y, Mori H, Masuyama N, Ishiguro S, Yachie N, Arakawa K. Complete Genome Sequence of Psychrobacter sp. Strain KH172YL61, Isolated from Deep-Sea Sediments in the Nankai Trough, Japan. Microbiology Resource Announcements 8:e00326-19 (2019)

Mori H, Evans-Yamamoto D, Ishiguro S, Tomita M, and Yachie N. Fast and global detection of periodic sequence repeats in large genomic resources. Nucleic Acid Research 47(2):e8 (2018)

Yachie N, Robotic Biology Consortium (D. Evans-Yamamoto was involved in the IT group), and Natsume T. Robotic Crowd Biology: LabDroids accelerates life science experiments. Nature Biotechnology 35(4):310-312 (2017)