PhD Student / Protein-protein interaction
e-mail: angel-fernando.cisneros-caballero.1 [at] ulaval.ca
Ever since I was young, I have been highly curious and willing to learn about different areas in science. Throughout my undergraduate degree in Biotechnological Engineering at the Monterrey Institute of Technology and Higher Education in Mexico City, I participated in several internships in different Mexican research institutes, namely the National Institute for Respiratory Diseases, the National Institute of Genomic Medicine, and the National Institute of Psychiatry, as well as the Institut de Biologie Intégrative et des Systèmes in Québec City. Working in different laboratories led me to develop interdisciplinary skills and introduced me to the field of bioinformatics, which I believe will continue to develop at a very accelerated pace and allow for an increased understanding of biological processes. I finished my undergraduate degree in December 2016, and then I decided to return to Québec City to continue working in Christian Landry’s laboratory. In September 2017, I started a Master’s Degree in Biochemistry with a concentration in Bioinformatics at Laval University. In May 2019, I advanced to a PhD in Biochemistry, still in Christian’s laboratory.
I am particularly interested in the evolution of protein-protein interactions after gene duplication. Duplications can have diverse effects, such as direct increases in the abundance of the produced protein and the emergence of heteromers that share the structure of ancestral homomers. Thus, my doctoral project aims to reveal how changes in protein abundance modify the fitness landscape of proteins and the long-term fate of the interaction profiles of duplicated proteins.