Vacancies

3 years postdoc in evolutionary systems biology at Université Laval

We are looking for a recent PhD graduate to join our group and lead a project in evolutionary systems biology. Our lab is in Québec City at Université Laval in Canada (https://landrylab.ibis.ulaval.ca/). We are an international and multidisciplinary team addressing various questions related to molecular evolution using systems biology approaches.

The project will be fully developed with the candidate. It will address questions related to the evolution of proteins involved in cell signalling following gene duplication using high-throughput gene editing and phenotyping approaches.

Cellular systems are constantly perturbed by changes in their environment and by changes in their internal conditions. How cells respond to perturbations will determine their long-term success. We are particularly interested in how proteins accomplish their functions when mutations occur, how they change the relationships among proteins and how these changes ultimately affect fitness. We are examining these questions using synthetic biology approaches to manipulate and engineer genomes to probe the effect of mutations on cellular signalling networks. We also study the modification of entire proteins, binding domains and short linear motifs (SLiMs) by Deep Mutational Scanning and genome editing to find how and why specific changes affect fitness while others do not.

We seek a recent PhD holder (less than 5 years ago) from a biochemistry, cell biology, molecular biology or genomics training program or a related discipline. A basic knowledge of bioinformatics (R or Python programming) would be a strong asset. No previous training in evolution is required. Having published as first author at the moment of application is necessary.

The starting date is September 2025, but is flexible. Applications are reviewed as they come.

See our recent publications in evolutionary systems biology by PhD students and postdoctoral fellows in our lab.

https://pubmed.ncbi.nlm.nih.gov/39146405/

https://pubmed.ncbi.nlm.nih.gov/39934115/

https://pubmed.ncbi.nlm.nih.gov/39964731/

https://pubmed.ncbi.nlm.nih.gov/36735790/

https://pubmed.ncbi.nlm.nih.gov/39537897/

https://pubmed.ncbi.nlm.nih.gov/39256561/

https://pubmed.ncbi.nlm.nih.gov/38499674/

If you are interested, please send your CV and a statement of interest to: landrylaboratory@gmail.com. We will get back to you if we need more information.