Johan Hallin, PhD
Postdoctoral fellow / Evolutionary systems biology
e-mail: johan-henning.hallin.1 [at] ulaval.ca
Biography
I found my way into research during my bachelor’s degree in biology doing large scale experimental evolution in the team of Jonas Warringer at the University of Gothenburg. In this project I was investigating the reproducibility of evolution as well as aiding in the development of a phenotyping platform. From there I continued with Jonas during my Master’s, looking into the effect of standing genetic variation on the speed of evolution. During this time, I acquired an Erasmus scholarship to work with Gianni Liti at the IRCAN in Nice allowing me to further improve my molecular biology skills. I was granted the opportunity to enroll in the Labex Signalife PhD program in Nice and I started my PhD in Gianni Liti’s lab, focusing my efforts on the relationship between genotype and phenotype. I am now a postdoctoral fellow with Christian Landry, using my expertise in yeast genetics, molecular biology, high throughput experiments and data analysis to answer questions about de novo gene formation.
Research interests
My interests extend to most corners of genetics. However, I have a predisposition towards evolution and genotype to phenotype relations. My current research focuses on the mysterious origination of new genes from non-coding sequences, a previously unrecognized cog in the evolutionary machinery that is gaining ground.
Publications
Vigne P, Gimond C, Ferrari C, Vielle A, Hallin J, Pino-Querido A, Mouridi SE, Mignerot L, Frøkjær-Jensen C, Boulin T, Teotónio H, Braendle C, A single-nucleotide change underlies the genetic assimilation of a trait. Science Advances 7 (6), eabd9941 (2020)
Barré B, Hallin J, Yue J, Persson K, Mikhalev E, Irizar A, Holt S, Thompson D, Molin M, Warringer J, Liti G, Intragenic repeat expansion in the cell wall protein gene HPF1 controls yeast chronological aging. Genome Research 30 (5), 697-710 (2020)
Hallin J, Cisneros AF, Hénault M, Fijarczyk A, Dandage R, Bautista C, & Landry CR, Similarities in biological processes can be used to bridge ecology and molecular biology. Evolutionary Applications 13 (6), 1335-1350 (2020)
Hallin J, Landry CR, Regulation plays a multifaceted role in the retention of gene duplicates. PLOS Biology 17 (11), e3000519 (2019)
Durand E, Gagnon-Arsenault I, Hallin J, Hatin I, Dubé A, Nielly-Thibault L, Namy O and Landry CR, Turnover of ribosome-associated transcripts from de novo ORFs produces gene-like characteristics available for de novo gene emergence in wild yeast populations. Genome Research 29 (6), 932-943 (2019)
Yue JX, Li J, Aigrain L, Hallin J, Persson K, Oliver K, Bergström A, Coupland P, Warringer J, Lagomarsino MC, Fischer G, Durbin R & Liti G, Contrasting evolutionary genome dynamics between domesticated and wild yeasts. Nature Genetics 49:913-924 (2017)
Zackrisson M, Hallin J, Ottosson LG, Dahl P, Fernandez-Parada E, Ländström E, Fernandez-Ricaud L, Kaferle P, Skyman A, Stenberg S, Omholt S, Petrovič U, Warringer J & Blomberg A, Scan-o-matic: high-resolution microbial phenomics at a massive scale. G3: Genes, Genomes, Genetics 6:3003-3014 (2016)
Märtens* K, Hallin* J, Warringer J, Liti G & Parts L, Predicting quantitative traits from genome and phenome with near perfect accuracy. Nature Communications 7:11512 (2016)
Hallin* J, Märtens* K, Young AI, Zackrisson M, Salinas F, Parts L, Warringer J & Liti G, Powerful decomposition of complex traits in a diploid model. Nature Communications 7:13311 (2016)
Vázquez-García I, Salinas F, Li J, Fischer A, Barré B, Hallin J, Bergström A, Alonso-Perez E, Warringer J, Mustonen V & Liti G, Clonal heterogeneity influences the fate of new adaptive mutations. Cell Reports 21:732-744 (2017)
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