Ajeya Roy

PhD Student / Evolutionary systems biology
e-mail:
ajeya.roy.1 [at] ulaval.ca

Biography

I grew up in Kolkata, West Bengal, India. Since a young age, I enjoyed Science classes, and after high school, I got an opportunity to pursue an integrated BS-MS degree in Basic Sciences at the Indian Institute of Science Education and Research (IISER) Tirupati, India. Throughout the duration of the degree, I took courses from multiple disciplines, including Biology, Physics, Chemistry, Mathematics, and Computer Science. Eventually, during my Master’s, I took Biology as my major and completed my Master’s thesis, where I studied the role of pre-replication complex proteins in kinetochore stabilisation using the budding yeast, Saccharomyces cerevisiae, as a model organism. During my Master’s project, I gradually became very interested in studying biological systems using computational approaches. Coming from an interdisciplinary background with varied interests, I decided to join the Computational Biophysics Lab at IISER Tirupati after my graduation. There, I worked as a Junior Research Fellow and studied disease-causing intrinsically disordered proteins and tried to come up with novel methods of targeting them using computational drug discovery and molecular dynamics simulations. In fall 2026, I joined the Landry Lab to pursue my PhD, and here I will be studying the effects of combinations of mutations, with an emphasis on intragenic complementation, using both computational and experimental approaches.

Research interests

I am broadly interested in topics lying at the intersection of protein evolution, structural biology, and computer science. For my PhD, I will focus on studying the molecular mechanisms underlying compensatory mutations, using both homomeric and multimeric proteins as model systems.

Outside the lab, I enjoy music and jamming sessions, and I also love to travel to new places and experience different cultures. I am also fond of cooking and trying out new recipes.

Publications