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Nickname : JB

Seasons : 2010-

website : http://www.jeanbaptisteleducq.com/

Jean-Baptiste Leducq
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English
Biography
I come from Calais (North of France) where I started my studies in biology (Bachelor’s degree in 2004, Université du Littoral-Côte-d’Opale), followed by a Master’s degree in Environment (2006) and a PhD in Population Genetics (2010) in Lille (Université Lille 1, France) under the direction of Prof. Xavier Vekemans and Dr. Sylvain Billiard (Lab. Génétique et Évolution des Populations Végétales). I am Post Doc in Evolutionary Systems Biology in Dr. Christian Landry’s laboratory since September 2010. I have expertise in genome analysis, population genetics, molecular biology, high throughput phenotyping, field and in situ experiments, population sampling, microbiology, botany, scientific vulgarization, communication and illustration, and the training of yound scientists.
I give courses to bachelor and master students in Ecology and I am interested in teaching Evolutionary Biology, Botany, Mycology and Population Genetics.
My other hobbies are cooking, gardening, music, literature and cello.

Research project
I am using a systemic approach to investigate historical, biological, adaptive and biogeographical events leading to speciation, at any organization level of life.
At a theoretical and empirical level, I was first interested in the effect of the reproduction system and of demographic and historical processes on the population dynamics of two plant species with contrasted ecology: Arabidopsis halleri in a fundamental context and Biscutella neustriaca in a conservation purpose.
Since more recently, I am interested in applying a population genetics and genomics approach to the most underrated Eukaryotic phylum: Fungi. Natural populations of the yeast Saccharomyces paradoxus are the ideal model to study the genomic imprint of great biogeographical changes, key processes of speciation and adaptation to climatic and trophic conditions.
Always using Saccharomyces as model, I am interested in evolutionary processes modulating protein interaction networks, especially the way they can diverge between close species and be reshuffled in interspecific hybrids.

Publications

Rochette S*, G Diss*, M Filteau, J-B Leducq, AK Dubé et al. Genome-wide protein-protein interaction screening by Protein-fragment Complementation Assay (PCA) in living cells. Journal of Visualized Experiments (in press)

Charron G*, J-B Leducq* & CR Landry. Chromosomal variation segregates within incipient species and correlate with reproductive isolation. Molecular Ecology 23(17): 4362-4372

Leducq J-B, CC Gosset, R Gries, K Calin, E Schmitt et al. Self-incompatibility in Brassicaceae: identification and characterization of SRK-like sequences linked to the S-locus in the tribe Biscutelleae. G3 (in press)

Leducq J-B. Ecological genomics of adaptation and speciation in fungi. Adv Exp Medi. & Bio 781: 49-72

Leducq J-B*, G Charron*, P Samani, AK Dube, K Sylvester et al. Local climatic adaptation in a widespread microorganism. Proc Royal Soc B 281(1777): 20132472

Charron G*, J-B Leducq*, C Bertin, AK Dube & CR Landry. Exploring the northern limit of the distribution of Saccharomyces cerevisiae and Saccharomyces paradoxus in North America. FEMS Yeast Res 14(2): 281-288

2013
Diss G*, M Filteau*, L Freschi*, J-B Leducq*, S Rochette* et al. Integrative avenues for exploring the dynamics and evolution of protein interaction networks. Curr Opin Biotechnol 24(4): 775-783

Leducq J-B, C Siniarsky, C Gosset, C Godé, M Poiret et al. Intriguing small-scale spatial distribution of chloropastic and nuclear diversity in the endangered plant Biscutella neustriaca (Brassicaceae). Conservation Genetics 14(1): 65-77

2012
Leducq J-B, G Charron, G Diss, I Gagnon-Arsenault, AK Dube et al. Evidence for the robustness of protein complexes to inter-species hybridization. PLoS genetics 8(12): e1003161

2011
El Chartouni L, B Tisserant, A Siah, F Duyme, J-B Leducq et al. Genetic diversity and population structure in French populations of Mycosphaerella graminicola. Mycologia 103(4): 764-774

Leducq J-B*, V Llaurens*, V Castric, P Saumitou-Laprade, OJ Hardy et al. Effect of balancing selection on spatial genetic structure within populations: theoretical investigations on the self-incompatibility locus and empirical studies in Arabidopsis halleri. Heredity 106(2): 319-329

2010
Leducq J-B, CC Gosset, M Poiret, F Hendoux, X Vekemans et al. An experimental study of the S-Allee effect in the self-incompatible plant Biscutella neustriaca. Conservation Genetics 11(2): 497-508

2008
Llaurens V, S Billiard, J-B Leducq, V Castric, EK Klein et al. Does frequency-dependent selection with complex dominance interactions accurately predict allelic frequencies at the self-incompatibility locus in Arabidopsis halleri? Evolution 62(10): 2545-2557