Johan H – Bio

English

Johan Hallin, PhD

Postdoctoral fellow
Evolutionary systems biology

Biography

I found my way into research during my bachelor’s degree in biology doing large scale experimental evolution in the team of Jonas Warringer at the University of Gothenburg. In this project I was investigating the reproducibility of evolution as well as aiding in the development of a phenotyping platform. From there I continued with Jonas during my Master’s, looking into the effect of standing genetic variation on the speed of evolution. During this time, I acquired an Erasmus scholarship to work with Gianni Liti at the IRCAN in Nice allowing me to further improve my molecular biology skills. I was granted the opportunity to enroll in the Labex Signalife PhD program in Nice and I started my PhD in Gianni Liti’s lab, focusing my efforts on the relationship between genotype and phenotype. I am now a postdoctoral fellow with Christian Landry, using my expertise in yeast genetics, molecular biology, high throughput experiments and data analysis to answer questions about de novo gene formation.

Research interests
 
My interests extend to most corners of genetics. However, I have a predisposition towards evolution and genotype to phenotype relations. My current research focuses on the mysterious origination of new genes from non-coding sequences, a previously unrecognized cog in the evolutionary machinery that is gaining ground.

Publications

Yue JX, Li J, Aigrain L, Hallin J, Persson K, Oliver K, Bergström A, Coupland P, Warringer J, Lagomarsino MC, Fischer G, Durbin R & Liti G, Contrasting evolutionary genome dynamics between domesticated and wild yeasts. Nature Genetics 49:913-924 (2017)

Zackrisson M, Hallin J, Ottosson LG, Dahl P, Fernandez-Parada E, Ländström E, Fernandez-Ricaud L, Kaferle P, Skyman A, Stenberg S, Omholt S, Petrovič U, Warringer J & Blomberg A, Scan-o-matic: high-resolution microbial phenomics at a massive scale. G3: Genes, Genomes, Genetics 6:3003-3014 (2016)

Märtens* K, Hallin* J, Warringer J, Liti G & Parts L, Predicting quantitative traits from genome and phenome with near perfect accuracy. Nature Communications 7:11512 (2016)

Hallin* J, Märtens* K, Young AI, Zackrisson M, Salinas F, Parts L, Warringer J & Liti G, Powerful decomposition of complex traits in a diploid model. Nature Communications 7:13311 (2016)

Vázquez-García I, Salinas F, Li J, Fischer A, Barré B, Hallin J, Bergström A, Alonso-Perez E, Warringer J, Mustonen V & Liti G, Clonal heterogeneity influences the fate of new adaptive mutations. Cell Reports 21:732-744 (2017)

Website

https://j-hallin.github.io/

Français

Johan Hallin, PhD 

Postdoctorant
Biologie évolutive des systèmes

Biographie

J’ai trouvé ma voie en recherche lors de mon baccalauréat en biologie en faisant de l’évolution expérimentale à grande échelle dans l’équipe de Jonas Warringer à l’Université de Gothenburg. J’y ai étudié la reproductibilité de l’évolution et j’ai participé au développement d’une plateforme de phénotypage. J’ai continué avec Jonas pendant ma maîtrise en examinant l’effet de la variation génétique sur la vitesse de l’évolution. Pendant ce temps, j’ai obtenu une bourse Erasmus pour travailler avec Gianni Liti à l’IRCAN de Nice, ce qui m’a permis d’améliorer mes compétences en biologie moléculaire. J’ai eu l’opportunité de m’inscrire au programme de doctorat Labex Signalife à Nice et j’ai commencé mon doctorat dans le laboratoire de Gianni Liti, concentrant mes efforts sur la relation entre le génotype et le phénotype. Je suis actuellement postdoctorant avec Christian Landry, où j’utilise mon expertise en génétique des levures, en biologie moléculaire, en expériences à haut débit et en analyse de données pour répondre à des questions sur la formation de novo de gènes.

Intérêts de recherche

Mes intérêts englobent toutes les facettes de la génétique. Cependant, j’ai un penchant particulier pour l’évolution et les relations génotype-phénotype. Mes recherches actuelles se concentrent sur l’origine mystérieuse de nouveaux gènes issus de séquences non codantes ; un rouage jusque-là méconnu dans la machinerie évolutive, mais qui gagne du terrain.

Publications

Yue JX, Li J, Aigrain L, Hallin J, Persson K, Oliver K, Bergström A, Coupland P, Warringer J, Lagomarsino MC, Fischer G, Durbin R & Liti G, Contrasting evolutionary genome dynamics between domesticated and wild yeasts. Nature Genetics 49:913-924 (2017)

Zackrisson M, Hallin J, Ottosson LG, Dahl P, Fernandez-Parada E, Ländström E, Fernandez-Ricaud L, Kaferle P, Skyman A, Stenberg S, Omholt S, Petrovič U, Warringer J & Blomberg A, Scan-o-matic: high-resolution microbial phenomics at a massive scale. G3: Genes, Genomes, Genetics 6:3003-3014 (2016)

Märtens* K, Hallin* J, Warringer J, Liti G & Parts L, Predicting quantitative traits from genome and phenome with near perfect accuracy. Nature Communications 7:11512 (2016)

Hallin* J, Märtens* K, Young AI, Zackrisson M, Salinas F, Parts L, Warringer J & Liti G, Powerful decomposition of complex traits in a diploid model. Nature Communications 7:13311 (2016)

Vázquez-García I, Salinas F, Li J, Fischer A, Barré B, Hallin J, Bergström A, Alonso-Perez E, Warringer J, Mustonen V & Liti G, Clonal heterogeneity influences the fate of new adaptive mutations. Cell Reports 21:732-744 (2017)

Site web

https://j-hallin.github.io/