Research opportunities

October 30th, 2017

Postdoctoral position in Evolutionary Cell Biology at Université Laval (Quebec City, Canada)

A postdoctoral position (2 years) is available in the Landry Laboratory (http://landrylab.ibis.ulaval.ca). The Landry laboratory is a very dynamic, international and interdisciplinary research group with broad interests in systems biology, molecular evolution, bioinformatics and ecological genomics.  The ideal applicant would have a strong expertise in molecular biology, biochemistry, or proteomics with interest for and/or basic skills in bioinformatics (Python, R). The projects are mainly experimental but candidates with strong computational backgrounds who are willing to learn and perform experimental research are encouraged to apply.  Previous work in yeast genetics and genomics would be an asset. Potential research topics are related to recently published work (see below) and include, but are not limited to, the evolution and function of new genes, compensatory evolution and the organization and evolution of protein-protein interaction networks.

Université Laval is one of the most important research universities in Canada and is located in Quebec City (https://en.wikipedia.org/wiki/Quebec_City), a lively city with a vibrant culture that offers an exceptional quality of life.

Interested applicants should send a CV, a list of publications, a statement of interest (1 page) and the name of three referees in a single PDF file to landrylaboratory@gmail.com. The positions will remain available until filled.  Starting dates could be between January 2018 and July 2018.

Recent representative publications:

Marsit S, Leducq JB, Durand É, Marchant A, Filteau M, Landry CR. Evolutionary biology through the lens of budding yeast comparative genomics. Nat Rev Genet.2017 Oct;18(10):581-598.

Diss G, Gagnon-Arsenault I, Dion-Coté AM, Vignaud H, Ascencio DI, Berger CM, Landry CR. Gene duplication can impart fragility, not robustness, in the yeast protein interaction network. Science. 2017 Feb 10;355(6325):630-634.

Caron D, Byrne DP, Thebault P, Soulet D, Landry CR, Eyers PA, Elowe S. Mitotic phosphotyrosine network analysis reveals that tyrosine phosphorylation regulates Polo-like kinase 1 (PLK1). Sci Signal. 2016 Dec 13;9(458):rs14.

Leducq JB, Nielly-Thibault L, Charron G, Eberlein C, Verta JP, Samani P,Sylvester K, Hittinger CT, Bell G, Landry CR. Speciation driven by hybridization and chromosomal plasticity in a wild yeast. Nat Microbiol. 2016 Jan 11;1:15003.

Filteau M, Hamel V, Pouliot MC, Gagnon-Arsenault I, Dubé AK, Landry CR. Evolutionary rescue by compensatory mutations is constrained by genomic and environmental backgrounds. Mol Syst Biol. 2015 Oct 12;11(10):832

Filteau M, Diss G, Torres-Quiroz F, Dubé AK, Schraffl A, Bachmann VA, Gagnon-Arsenault I, Chrétien AÈ, Steunou AL, Dionne U, Côté J, Bisson N, Stefan E, Landry CR. Systematic identification of signal integration by protein kinase A. Proc Natl Acad Sci U S A. 2015 Apr 7;112(14):4501-6.

Nguyen Ba AN, Strome B, Hua JJ, Desmond J, Gagnon-Arsenault I, Weiss EL, Landry CR, Moses AM. Detecting functional divergence after gene duplication through evolutionary changes in posttranslational regulatory sequences. PLoS Comput Biol. 2014 Dec 4;10(12):e1003977.

Goldman A, Roy J, Bodenmiller B, Wanka S, Landry CR, Aebersold R, Cyert MS. The calcineurin signaling network evolves via conserved kinase-phosphatase modules that transcend substrate identity. Mol Cell. 2014 Aug 7;55(3):422-435.